Viral alpha-synuclein knockdown prevents spreading synucleinopathy

The accumulation of aggregated alpha-synuclein (α-syn) in Parkinson's disease, dementia with Lewy bodies and multiple system atrophy is thought to involve a common prion-like mechanism, whereby misfolded α-syn provides a conformational template for further accumulation of pathological α-syn. We...

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Detalles Bibliográficos
Autores principales: Menon, Sindhu, Kofoed, Rikke H, Nabbouh, Fadl, Xhima, Kristiana, Al-Fahoum, Yasmeen, Langman, Tammy, Mount, Howard T J, Shihabuddin, Lamya S, Sardi, S Pablo, Fraser, Paul E, Watts, Joel C, Aubert, Isabelle, Tandon, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576194/
https://www.ncbi.nlm.nih.gov/pubmed/34761222
http://dx.doi.org/10.1093/braincomms/fcab247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576194/
https://www.ncbi.nlm.nih.gov/pubmed/34761222
http://dx.doi.org/10.1093/braincomms/fcab247

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