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Aneuploidy facilitates dysplastic and tumorigenic phenotypes in the Drosophila gut

Aneuploidy has been strongly linked to cancer development, and published evidence has suggested that aneuploidy can have an oncogenic or a tumor suppressor role depending on the tissue context. Using the Drosophila midgut as a model, we have recently described that adult intestinal stem cells (ISCs)...

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Detalles Bibliográficos
Autores principales: Brás, Rita, Monteiro, Augusta, Sunkel, Claudio E., Resende, Luís Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576263/
https://www.ncbi.nlm.nih.gov/pubmed/33948620
http://dx.doi.org/10.1242/bio.058623