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Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction

AIMS: Pharmacological termination of atrial fibrillation (AF) remains a challenge due to limited efficacy and potential ventricular proarrhythmic effects of antiarrhythmic drugs. SK channels are proposed as atrial-specific targets in the treatment of AF. Here, we investigated the effects of the new...

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Detalles Bibliográficos
Autores principales: Gatta, Giulia, Sobota, Vladimir, Citerni, Carlotta, Diness, Jonas Goldin, Sørensen, Ulrik S, Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, Stef, Kuiper, Marion, Verheule, Sander, Schotten, Ulrich, van Hunnik, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576281/
https://www.ncbi.nlm.nih.gov/pubmed/34080619
http://dx.doi.org/10.1093/europace/euab125