Broad-Spectrum Inhibitor of Bacterial Polyphosphate Homeostasis Attenuates Virulence Factors and Helps Reveal Novel Physiology of Klebsiella pneumoniae and Acinetobacter baumannii

Acinetobacter baumannii and Klebsiella pneumoniae currently rank amongst the most antibiotic-resistant pathogens, responsible for millions of infections each year. In the wake of this crisis, anti-virulence therapeutics targeting bacterial polyphosphate (polyP) homeostasis have been lauded as an att...

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Detalles Bibliográficos
Autores principales: Roberge, Nathan, Neville, Nolan, Douchant, Katya, Noordhof, Curtis, Boev, Nadejda, Sjaarda, Calvin, Sheth, Prameet M., Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576328/
https://www.ncbi.nlm.nih.gov/pubmed/34764949
http://dx.doi.org/10.3389/fmicb.2021.764733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576328/
https://www.ncbi.nlm.nih.gov/pubmed/34764949
http://dx.doi.org/10.3389/fmicb.2021.764733

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