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Genetics and Clinical Characteristics of PPARγ Variant-Induced Diabetes in a Chinese Han Population

OBJECTIVES: PPARγ variants cause lipodystrophy, insulin resistance, and diabetes. This study aimed to determine the relationship between PPARγ genotypes and phenotypes and to explore the pathogenesis of diabetes beyond this relationship. METHODS: PPARγ2 exons in 1,002 Chinese patients with early-ons...

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Detalles Bibliográficos
Autores principales: Gong, Siqian, Han, Xueyao, Li, Meng, Cai, Xiaoling, Liu, Wei, Luo, Yingying, Zhang, Si-min, Zhou, Lingli, Ma, Yumin, Huang, Xiuting, Li, Yufeng, Zhou, Xianghai, Zhu, Yu, Wang, Qiuping, Chen, Ling, Ren, Qian, Zhang, Ping, Ji, Linong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576343/
https://www.ncbi.nlm.nih.gov/pubmed/34764936
http://dx.doi.org/10.3389/fendo.2021.677130