Endothelial Dec1-PPARγ Axis Impairs Proliferation and Apoptosis Homeostasis Under Hypoxia in Pulmonary Arterial Hypertension

Background: The hypoxia-induced pro-proliferative and anti-apoptotic characteristics of pulmonary arterial endothelial cells (PAECs) play critical roles in pulmonary vascular remodeling and contribute to hypoxic pulmonary arterial hypertension (PAH) pathogenesis. However, the mechanism underlying th...

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Detalles Bibliográficos
Autores principales: Li, Xiaoming, Liu, Chengcheng, Qi, Wenwen, Meng, Qiu, Zhao, Hui, Teng, Zhenxiao, Xu, Runtong, Wu, Xinhao, Zhu, Fangyuan, Qin, Yiming, Zhao, Miaoqing, Xu, Fenglei, Xia, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576361/
https://www.ncbi.nlm.nih.gov/pubmed/34765605
http://dx.doi.org/10.3389/fcell.2021.757168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576361/
https://www.ncbi.nlm.nih.gov/pubmed/34765605
http://dx.doi.org/10.3389/fcell.2021.757168

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