A Screen of Autophagy Compounds Implicates the Proteasome in Mammalian Aminoglycoside-Induced Hair Cell Damage

Introduction: Autophagy is a degradative pathway to safely break down and recycle dysfunctional cellular components. There is prior evidence of autophagy participation during hair cell (HC) damage. Our goal was to screen compounds targeting different aspects of autophagy for their effects on HC loss...

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Detalles Bibliográficos
Autores principales: Draf, Clara, Wyrick, Taylor, Chavez, Eduardo, Pak, Kwang, Kurabi, Arwa, Leichtle, Anke, Dazert, Stefan, Ryan, Allen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576371/
https://www.ncbi.nlm.nih.gov/pubmed/34765606
http://dx.doi.org/10.3389/fcell.2021.762751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576371/
https://www.ncbi.nlm.nih.gov/pubmed/34765606
http://dx.doi.org/10.3389/fcell.2021.762751

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