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Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex

Weakness and atrophy are key features of Duchenne muscular dystrophy (DMD). Dystrophin is one of the many proteins within the dystrophin glycoprotein complex (DGC) that maintains plasmalemmal integrity and cellular homeostasis. The dystrophin-deficient mdx mouse is also predisposed to weakness, part...

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Detalles Bibliográficos
Autores principales: Baumann, Cory W., Lindsay, Angus, Sidky, Sylvia R., Ervasti, James M., Warren, Gordon L., Lowe, Dawn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576390/
https://www.ncbi.nlm.nih.gov/pubmed/34764884
http://dx.doi.org/10.3389/fphys.2021.757121