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Novel Allele Detection Tool Benchmark and Application With Antibody Repertoire Sequencing Dataset

Detailed knowledge of the diverse immunoglobulin germline genes is critical for the study of humoral immunity. Hundreds of alleles have been discovered by analyzing antibody repertoire sequencing (Rep-seq or Ig-seq) data via multiple novel allele detection tools (NADTs). However, the performance of...

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Detalles Bibliográficos
Autores principales: Yang, Xiujia, Zhu, Yan, Chen, Sen, Zeng, Huikun, Guan, Junjie, Wang, Qilong, Lan, Chunhong, Sun, Deqiang, Yu, Xueqing, Zhang, Zhenhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576399/
https://www.ncbi.nlm.nih.gov/pubmed/34764956
http://dx.doi.org/10.3389/fimmu.2021.739179