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From Pancreatic β-Cell Gene Networks to Novel Therapies for Type 1 Diabetes

Completion of the Human Genome Project enabled a novel systems- and network-level understanding of biology, but this remains to be applied for understanding the pathogenesis of type 1 diabetes (T1D). We propose that defining the key gene regulatory networks that drive β-cell dysfunction and death in...

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Detalles Bibliográficos
Autores principales: Eizirik, Decio L., Szymczak, Florian, Alvelos, Maria Inês, Martin, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576417/
https://www.ncbi.nlm.nih.gov/pubmed/34417266
http://dx.doi.org/10.2337/dbi20-0046