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Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy
OBJECTIVE: To summarize the roles of AKT-mTOR signaling in the regulation of the DNA damage response and PD-L1 expression in cancer cells, and propose a novel strategy of targeting AKT-mTOR signaling in combination with radioimmunotherapy in the era of cancer immunotherapy BACKGROUND: Immunotherapy...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576660/ https://www.ncbi.nlm.nih.gov/pubmed/34790802 http://dx.doi.org/10.21037/atm-21-4544 |