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Narrative review of emerging roles for AKT-mTOR signaling in cancer radioimmunotherapy

OBJECTIVE: To summarize the roles of AKT-mTOR signaling in the regulation of the DNA damage response and PD-L1 expression in cancer cells, and propose a novel strategy of targeting AKT-mTOR signaling in combination with radioimmunotherapy in the era of cancer immunotherapy BACKGROUND: Immunotherapy...

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Detalles Bibliográficos
Autores principales: Shen, Changxian, He, Yuqi, Chen, Qiang, Feng, Haihua, Williams, Terence M., Lu, Yuanzhi, He, Zhengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576660/
https://www.ncbi.nlm.nih.gov/pubmed/34790802
http://dx.doi.org/10.21037/atm-21-4544