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Transcription factor CDX2 up-regulates proto-oncogenic miR-744 via a promoter activation mechanism in non-small-cell lung cancer

BACKGROUND: The role of caudal-related homeobox 2 (CDX2) in the pathogenesis of non-small cell lung cancer (NSCLC) is unclear. The purpose of this study was to investigate the mRNA (message RNA) expression of CDX2 in NSCLC, and to determine its relationship with miR-744 (microRNA744) and its potenti...

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Detalles Bibliográficos
Autores principales: Sha, Zhou, Hao, Song, Long, Fengjiao, Wei, Yajun, Chen, Shaoyi, Li, Ting, Yi, Lina, Hu, Liyang, Lin, Zhong, Xian, Jianzhong, Pei, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576675/
https://www.ncbi.nlm.nih.gov/pubmed/34790744
http://dx.doi.org/10.21037/atm-21-4526