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Lupeol reduces M1 macrophage polarization to attenuate immunologic dissonance and fatty acid deposition in rats with diet-induced metabolic syndrome

BACKGROUND: This study aimed to investigate whether lupeol could inhibit the inflammatory mediators associated with the regulation of macrophage phenotypes and functions in rats with diet-induced metabolic syndrome (MS). METHODS: Forty specific-pathogen-free Sprague Dawley rats were fed a high-fat d...

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Detalles Bibliográficos
Autores principales: Li, Jin, Huang, Yuechen, Han, Yue, Wang, Jiafu, Zhang, Chun, Jiang, Jiuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576680/
https://www.ncbi.nlm.nih.gov/pubmed/34790740
http://dx.doi.org/10.21037/atm-21-4561