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AZD9291-resistant non-small cell lung cancer cell-derived exosomal lnc-MZT2A-5:1 induces the activation of fibroblasts

BACKGROUND: AZD9291 resistance is still a challenge in the treatment of non-small cell lung cancer (NSCLC) and fibroblasts in the tumor microenvironment (TME) play a key role in the malignant phenotype of NSCLC. The study aimed to investigate the role of exosomes derived from AZD9291-resistant cells...

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Detalles Bibliográficos
Autores principales: Song, Liwei, Qian, Gang, Huang, Jia, Chen, Tianxiang, Yang, Yunhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576687/
https://www.ncbi.nlm.nih.gov/pubmed/34790799
http://dx.doi.org/10.21037/atm-21-5186