Synergistic effect of chidamide and venetoclax on apoptosis in acute myeloid leukemia cells and its mechanism

BACKGROUND: Acute myeloid leukemia (AML) is a hematological malignancy with a low remission rate and high recurrence rate. Overexpression of the antiapoptotic protein Bcl-2 is associated with a lower overall survival rate in AML patients. Venetoclax (ABT199) is a selective inhibitor of Bcl-2 that ha...

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Detalles Bibliográficos
Autores principales: Li, Gangping, Li, Dongbei, Yuan, Fangfang, Cheng, Cheng, Chen, Lin, Wei, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576699/
https://www.ncbi.nlm.nih.gov/pubmed/34790781
http://dx.doi.org/10.21037/atm-21-5066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576699/
https://www.ncbi.nlm.nih.gov/pubmed/34790781
http://dx.doi.org/10.21037/atm-21-5066

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