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Inflammasome-mediated neurodegeneration following heart disease

BACKGROUND: Myocardial infarction (MI) has been suggested as a critical predisposing factor for Alzheimer’s disease (AD); however, the underlying mechanisms remain unknown. PYD domains-containing protein 3 (NLRP3) is a key factor to mediate inflammasome formation. Previous studies have shown that NL...

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Detalles Bibliográficos
Autores principales: Cheng, Kuan, Wang, Jingjing, Chen, Qingxing, Zhao, Gang, Pang, Yang, Xu, Ye, Ge, Junbo, Zhu, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576725/
https://www.ncbi.nlm.nih.gov/pubmed/34790766
http://dx.doi.org/10.21037/atm-21-4931