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Sulfuretted hydrogen ameliorates high dose glucose-induced podocyte apoptosis via orchestrating AMPK/mTOR cascade-mediated anti-apoptotic effects

BACKGROUND: Podocytes play a pivotal role in the glomerular filtration barrier and contribute to proteinuria and glomerulosclerosis through abnormal apoptosis. Longitudinal studies have indicated the protective properties of hydrogen sulfide (H(2)S) against neuronal cell apoptosis, whereas the biolo...

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Detalles Bibliográficos
Autores principales: Huang, Yong, Cheng, Jie, Zhou, Yehua, Zhang, Yanhui, Zhou, Shuhui, Li, Qingzhen, Peng, Lin, Wang, Maohong, Song, Weiguo, Wu, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576736/
https://www.ncbi.nlm.nih.gov/pubmed/34790792
http://dx.doi.org/10.21037/atm-21-5152