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Sulfuretted hydrogen ameliorates high dose glucose-induced podocyte apoptosis via orchestrating AMPK/mTOR cascade-mediated anti-apoptotic effects
BACKGROUND: Podocytes play a pivotal role in the glomerular filtration barrier and contribute to proteinuria and glomerulosclerosis through abnormal apoptosis. Longitudinal studies have indicated the protective properties of hydrogen sulfide (H(2)S) against neuronal cell apoptosis, whereas the biolo...
Autores principales: | Huang, Yong, Cheng, Jie, Zhou, Yehua, Zhang, Yanhui, Zhou, Shuhui, Li, Qingzhen, Peng, Lin, Wang, Maohong, Song, Weiguo, Wu, Guoqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576736/ https://www.ncbi.nlm.nih.gov/pubmed/34790792 http://dx.doi.org/10.21037/atm-21-5152 |
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