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Reducing l‐lactate release from hippocampal astrocytes by intracellular oxidation increases novelty induced activity in mice

Astrocytes are in control of metabolic homeostasis in the brain and support and modulate neuronal function in various ways. Astrocyte‐derived l‐lactate (lactate) is thought to play a dual role as a metabolic and a signaling molecule in inter‐cellular communication. The biological significance of lac...

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Detalles Bibliográficos
Autores principales: Vaccari Cardoso, Barbara, Shevelkin, Alexey V., Terrillion, Chantelle, Mychko, Olga, Mosienko, Valentina, Kasparov, Sergey, Pletnikov, Mikhail V., Teschemacher, Anja G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576740/
https://www.ncbi.nlm.nih.gov/pubmed/33400321
http://dx.doi.org/10.1002/glia.23960