The ethoxycarbonyl group as both activating and protective group in N-acyl-Pictet–Spengler reactions using methoxystyrenes. A short approach to racemic 1-benzyltetrahydroisoquinoline alkaloids

We present a systematic investigation on an improved variant of the N-acyl-Pictet–Spengler condensation for the synthesis of 1-benzyltetrahydroisoquinolines, based on our recently published synthesis of N-methylcoclaurine, exemplified by the total syntheses of 10 alkaloids in racemic form. Major adv...

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Detalles Bibliográficos
Autores principales: Keller, Marco, Sauvageot-Witzku, Karl, Geisslinger, Franz, Urban, Nicole, Schaefer, Michael, Bartel, Karin, Bracher, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576818/
https://www.ncbi.nlm.nih.gov/pubmed/34804241
http://dx.doi.org/10.3762/bjoc.17.183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576818/
https://www.ncbi.nlm.nih.gov/pubmed/34804241
http://dx.doi.org/10.3762/bjoc.17.183

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