AlBr(3)-Promoted stereoselective anti-hydroarylation of the acetylene bond in 3-arylpropynenitriles by electron-rich arenes: synthesis of 3,3-diarylpropenenitriles

Reactions of 3-arylpropynenitriles (ArC≡CCN) with electron-rich arenes (Ar′H, benzene and its polymethylated derivatives) under the action of aluminum bromide (AlBr(3), 6 equiv) at room temperature for 0.5–2 h result in the stereoselective formation of 3,3-diarylpropenenitriles (Ar(Ar′)C=CHCN) in yi...

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Detalles Bibliográficos
Autores principales: Gorbunova, Yelizaveta, Ryabukhin, Dmitry S, Vasilyev, Aleksander V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576820/
https://www.ncbi.nlm.nih.gov/pubmed/34804238
http://dx.doi.org/10.3762/bjoc.17.180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576820/
https://www.ncbi.nlm.nih.gov/pubmed/34804238
http://dx.doi.org/10.3762/bjoc.17.180

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