Leveraging Trifluoromethylated Benzyl Groups toward the Highly 1,2-Cis-Selective Glucosylation of Reactive Alcohols

[Image: see text] Here, we demonstrate that substitution of the benzyl groups of glucosyl imidate donors with trifluoromethyl results in a substantial increase in 1,2-cis-selectivity when activated with TMS-I in the presence of triphenylphosphine oxide. Stereoselectivity is dependent on the number o...

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Detalles Bibliográficos
Autores principales: Njeri, Dancan K., Valenzuela, Erik Alvarez, Ragains, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576833/
https://www.ncbi.nlm.nih.gov/pubmed/34677075
http://dx.doi.org/10.1021/acs.orglett.1c02947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576833/
https://www.ncbi.nlm.nih.gov/pubmed/34677075
http://dx.doi.org/10.1021/acs.orglett.1c02947

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