Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy

BACKGROUND: Africans exhibit great diversity in cytochrome P450 2B6 isoenzyme (CYP2B6), the major enzyme in efavirenz metabolism. AIM: We examined the frequency of two functional single nucleotide polymorphisms (SNPs) of the CYP2B6 pharmacogene in HIV-infected Nigerians on efavirenz-based antiretrov...

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Detalles Bibliográficos
Autores principales: Isaac, AO, Wetkos, DD, Oche, AO, Godwin, I, Phyllis, K, John, AC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576856/
https://www.ncbi.nlm.nih.gov/pubmed/33355828
http://dx.doi.org/10.4103/njcp.njcp_348_20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576856/
https://www.ncbi.nlm.nih.gov/pubmed/33355828
http://dx.doi.org/10.4103/njcp.njcp_348_20

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