Brain transcriptome analysis of a CLN2 mouse model as a function of disease progression

BACKGROUND: Neuronal ceroid lipofuscinoses, (NCLs or Batten disease) are a group of inherited, early onset, fatal neurodegenerative diseases associated with mutations in 13 genes. All forms of the disease are characterized by lysosomal accumulation of fluorescent storage material, as well as profoun...

Descripción completa

Detalles Bibliográficos
Autores principales: Domowicz, Miriam S., Chan, Wen-Ching, Claudio-Vázquez, Patricia, Gonzalez, Tatiana, Schwartz, Nancy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576919/
https://www.ncbi.nlm.nih.gov/pubmed/34749772
http://dx.doi.org/10.1186/s12974-021-02302-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576919/
https://www.ncbi.nlm.nih.gov/pubmed/34749772
http://dx.doi.org/10.1186/s12974-021-02302-z

Ejemplares similares