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N-Methyl-D-aspartate (NMDA) and cannabinoid CB(2) receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA receptors

BACKGROUND: The cannabinoid CB(2) receptor (CB(2)R), which is a target to afford neuroprotection, and N-methyl-D-aspartate (NMDA) ionotropic glutamate receptors, which are key in mediating excitatory neurotransmission, are expressed in both neurons and glia. As NMDA receptors are the target of curre...

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Detalles Bibliográficos
Autores principales: Rivas-Santisteban, Rafael, Lillo, Alejandro, Lillo, Jaume, Rebassa, Joan-Biel, Contestí, Joan S., Saura, Carlos A., Franco, Rafael, Navarro, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576920/
https://www.ncbi.nlm.nih.gov/pubmed/34749800
http://dx.doi.org/10.1186/s13195-021-00920-6