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DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma

BACKGROUND: Angiogenesis plays an important role in the occurrence, development and metastasis of hepatocellular carcinoma (HCC). According to previous studies, miR-378a participates in tumorigenesis and tumor metastasis, but its exact role in HCC angiogenesis remains poorly understood. METHODS: qRT...

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Detalles Bibliográficos
Autores principales: Zhu, Bin, Chen, Jun-Jie, Feng, Ying, Yang, Jun-Ling, Huang, Hua, Chung, Wen Yuan, Hu, Yi-Lin, Xue, Wan-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576931/
https://www.ncbi.nlm.nih.gov/pubmed/34749775
http://dx.doi.org/10.1186/s13046-021-02110-6