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RPD3 and UME6 are involved in the activation of PDR5 transcription and pleiotropic drug resistance in ρ(0) cells of Saccharomyces cerevisiae
BACKGROUND: In Saccharomyces cerevisiae, the retrograde signalling pathway is activated in ρ(0/−) cells, which lack mitochondrial DNA. Within this pathway, the activation of the transcription factor Pdr3 induces transcription of the ATP-binding cassette (ABC) transporter gene, PDR5, and causes pleio...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576940/ https://www.ncbi.nlm.nih.gov/pubmed/34753419 http://dx.doi.org/10.1186/s12866-021-02373-1 |