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Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine
BACKGROUND: Cancer is a somatic evolutionary disease and adenocarcinomas of the stomach and gastroesophageal junction (GC) may serve as a two-dimensional model of cancer expansion, in which tumor subclones are not evenly mixed during tumor progression but rather spatially separated and diversified....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576943/ https://www.ncbi.nlm.nih.gov/pubmed/34749812 http://dx.doi.org/10.1186/s13073-021-00975-y |