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Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine

BACKGROUND: Cancer is a somatic evolutionary disease and adenocarcinomas of the stomach and gastroesophageal junction (GC) may serve as a two-dimensional model of cancer expansion, in which tumor subclones are not evenly mixed during tumor progression but rather spatially separated and diversified....

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Detalles Bibliográficos
Autores principales: Röcken, Christoph, Amallraja, Anu, Halske, Christine, Opasic, Luka, Traulsen, Arne, Behrens, Hans-Michael, Krüger, Sandra, Liu, Anne, Haag, Jochen, Egberts, Jan-Hendrik, Rosenstiel, Philip, Meißner, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576943/
https://www.ncbi.nlm.nih.gov/pubmed/34749812
http://dx.doi.org/10.1186/s13073-021-00975-y