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Constructing germline research cohorts from the discarded reads of clinical tumor sequences
BACKGROUND: Hundreds of thousands of cancer patients have had targeted (panel) tumor sequencing to identify clinically meaningful mutations. In addition to improving patient outcomes, this activity has led to significant discoveries in basic and translational domains. However, the targeted nature of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576948/ https://www.ncbi.nlm.nih.gov/pubmed/34749793 http://dx.doi.org/10.1186/s13073-021-00999-4 |