Cargando…

Self-amplification of oxidative stress with tumour microenvironment-activatable iron-doped nanoplatform for targeting hepatocellular carcinoma synergistic cascade therapy and diagnosis

BACKGROUND: Hepatocellular carcinoma is insensitive to many chemotherapeutic agents. Ferroptosis is a form of programmed cell death with a Fenton reaction mechanism. It converts endogenous hydrogen peroxide into highly toxic hydroxyl radicals, which inhibit hepatocellular carcinoma progression. METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Qiao-Mei, Lu, Yuan-Fei, Zhou, Jia-Ping, Yang, Xiao-Yan, Wang, Xiao-Jie, Yu, Jie-Ni, Du, Yong-Zhong, Yu, Ri-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576982/
https://www.ncbi.nlm.nih.gov/pubmed/34749740
http://dx.doi.org/10.1186/s12951-021-01102-0