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Self-amplification of oxidative stress with tumour microenvironment-activatable iron-doped nanoplatform for targeting hepatocellular carcinoma synergistic cascade therapy and diagnosis
BACKGROUND: Hepatocellular carcinoma is insensitive to many chemotherapeutic agents. Ferroptosis is a form of programmed cell death with a Fenton reaction mechanism. It converts endogenous hydrogen peroxide into highly toxic hydroxyl radicals, which inhibit hepatocellular carcinoma progression. METH...
Autores principales: | Zhou, Qiao-Mei, Lu, Yuan-Fei, Zhou, Jia-Ping, Yang, Xiao-Yan, Wang, Xiao-Jie, Yu, Jie-Ni, Du, Yong-Zhong, Yu, Ri-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576982/ https://www.ncbi.nlm.nih.gov/pubmed/34749740 http://dx.doi.org/10.1186/s12951-021-01102-0 |
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