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Dysfunctional BTN3A together with deregulated immune checkpoints and type I/II IFN dictate defective interplay between pDCs and γδ T cells in melanoma patients, which impacts clinical outcomes

OBJECTIVES: pDCs and γδ T cells emerge as potent immune players participating in the pathophysiology of cancers, yet still remaining enigmatic while harbouring a promising potential for clinical translations. Despite strategic and closed missions, crosstalk between pDCs and γδ T cells has not been d...

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Detalles Bibliográficos
Autores principales: Girard, Pauline, Sosa Cuevas, Eleonora, Ponsard, Benedicte, Mouret, Stephane, Gil, Hugo, Col, Edwige, De Fraipont, Florence, Sturm, Nathalie, Charles, Julie, Manches, Olivier, Chaperot, Laurence, Aspord, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577077/
https://www.ncbi.nlm.nih.gov/pubmed/34786191
http://dx.doi.org/10.1002/cti2.1329