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Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells

Embryonic stem cells (ESCs) are progenitor cells that retain the ability to differentiate into various cell types and are necessary for tissue repair. Improving cell culture conditions to maintain the pluripotency of ESCs in vitro is an urgent problem in the field of regenerative medicine. Here, we...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wang, Xiaoxiao, Zhang, Xinbao, Zhang, Yan, Zhu, Zhenhua, Li, Yuting, Zhang, Meng, Ji, Junxiang, Yu, Yang, Ye, Shou-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577099/
https://www.ncbi.nlm.nih.gov/pubmed/34688658
http://dx.doi.org/10.1016/j.jbc.2021.101332