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Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8

A disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs (ADAMTS)8 is a secreted protease, which was recently implicated in pathogenesis of pulmonary arterial hypertension (PAH). However, the substrate repertoire of ADAMTS8 and regulation of its activity are incompletely under...

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Detalles Bibliográficos
Autores principales: Santamaria, Salvatore, Martin, Daniel R., Dong, Xiangyi, Yamamoto, Kazuhiro, Apte, Suneel S., Ahnström, Josefin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577114/
https://www.ncbi.nlm.nih.gov/pubmed/34687701
http://dx.doi.org/10.1016/j.jbc.2021.101323