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GABA(B1e) promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

Neurotransmitter receptors are involved in cancer progression. Among them, the heterodimeric GABA(B) receptor, activated by the main inhibitory neurotransmitter GABA, is composed of the transmembrane GABA(B1) and GABA(B2) subunits. The oncogenic role of the isoform GABA(B1e) (GB(1e)) containing only...

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Detalles Bibliográficos
Autores principales: Wei, Bo, Zhu, Yini, Yang, Peng, Han, Yong, Wang, Suyun, Wang, Xiaomei, Xia, Shuai, Song, Xiaoguang, Zhang, Zhongling, Wang, Sheng, Rondard, Philippe, Pin, Jean-Philippe, Jiang, Xinnong, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577127/
https://www.ncbi.nlm.nih.gov/pubmed/34778730
http://dx.doi.org/10.1016/j.isci.2021.103311