Cargando…

GABA(B1e) promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12

Neurotransmitter receptors are involved in cancer progression. Among them, the heterodimeric GABA(B) receptor, activated by the main inhibitory neurotransmitter GABA, is composed of the transmembrane GABA(B1) and GABA(B2) subunits. The oncogenic role of the isoform GABA(B1e) (GB(1e)) containing only...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Bo, Zhu, Yini, Yang, Peng, Han, Yong, Wang, Suyun, Wang, Xiaomei, Xia, Shuai, Song, Xiaoguang, Zhang, Zhongling, Wang, Sheng, Rondard, Philippe, Pin, Jean-Philippe, Jiang, Xinnong, Liu, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577127/ https://www.ncbi.nlm.nih.gov/pubmed/34778730 http://dx.doi.org/10.1016/j.isci.2021.103311

Ejemplares similares

Dual Role of the PTPN13 Tyrosine Phosphatase in Cancer
por: Mcheik, Soha, et al.
Publicado: (2020)

NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
por: Spalinger, Marianne R., et al.
Publicado: (2023)

Complex GABA(B) receptor complexes: how to generate multiple functionally distinct units from a single receptor
por: Xu, Chanjuan, et al.
Publicado: (2014)

The tyrosine phosphatase PTPN13/FAP-1 links calpain-2, TBI and tau tyrosine phosphorylation
por: Wang, Yubin, et al.
Publicado: (2017)

Protein Tyrosine Phosphatase SHP-2 (PTPN11) in Hematopoiesis and Leukemogenesis
por: Liu, Xia, et al.
Publicado: (2011)

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity
por: Michaloglou, Chrysiis, et al.
Publicado: (2013)

Structural basis of GABA(B) receptor–G(i) protein coupling
por: Shen, Cangsong, et al.
Publicado: (2021)

The Tyrosine Phosphatase Activity of PTPN22 Is Involved in T Cell Development via the Regulation of TCR Expression
por: Bai, Bin, et al.
Publicado: (2023)

A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2)
por: Duval, Romain, et al.
Publicado: (2015)

Tyrosine Phosphatases in the HER2-Directed Motility of Ovarian Cancer Cells: Involvement of PTPN12, ERK5 and FAK
por: Villa-Moruzzi, Emma
Publicado: (2011)

Protein tyrosine phosphatase PTPN22 +1858C/T polymorphism is associated with active vitiligo
por: GARCIA-MELENDEZ, MARTHA ELENA, et al.
Publicado: (2014)

The FERM and PDZ Domain-Containing Protein Tyrosine Phosphatases, PTPN4 and PTPN3, Are Both Dispensable for T Cell Receptor Signal Transduction
por: Bauler, Timothy J., et al.
Publicado: (2008)

Multifunctional roles of the autoimmune disease-associated tyrosine phosphatase PTPN22 in regulating T cell homeostasis
por: Salmond, Robert J, et al.
Publicado: (2015)

The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens
por: Clarke, Fiona, et al.
Publicado: (2018)

Protein tyrosine phosphatase PTPN22 regulates LFA-1 dependent Th1 responses
por: Sanchez-Blanco, Cristina, et al.
Publicado: (2018)

Association of Functional Polymorphism in Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) Gene with Vitiligo
por: Huraib, Ghaleb Bin, et al.
Publicado: (2020)

Protein tyrosine phosphatase PTPN3 promotes drug resistance and stem cell-like characteristics in ovarian cancer
por: Li, Shuqin, et al.
Publicado: (2016)

Structural insights into Noonan/LEOPARD syndrome-related mutants of protein-tyrosine phosphatase SHP2 (PTPN11)
por: Qiu, Wei, et al.
Publicado: (2014)

GABA(B) receptor upregulates fragile X mental retardation protein expression in neurons
por: Zhang, Wenhua, et al.
Publicado: (2015)

The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) R620W Functional Polymorphism in Psoriasis
por: Bin Huraib, Ghaleb, et al.
Publicado: (2018)

Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
por: Sood, Shatakshi, et al.
Publicado: (2016)

Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma
por: Nunes-Xavier, Caroline E., et al.
Publicado: (2019)

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein
por: Genera, Mariano, et al.
Publicado: (2021)

Structural basis of the activation of a metabotropic GABA receptor
por: Shaye, Hamidreza, et al.
Publicado: (2020)

A Loss-of-Function Screen for Phosphatases that Regulate Neurite Outgrowth Identifies PTPN12 as a Negative Regulator of TrkB Tyrosine Phosphorylation
por: Ambjørn, Malene, et al.
Publicado: (2013)

The tyrosine phosphatase Ptpn22 discriminates weak, self-peptide from strong agonist T cell receptor signals
por: Salmond, Robert J., et al.
Publicado: (2014)

The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization
por: Husedzinovic, Alma, et al.
Publicado: (2015)

Association of the protein tyrosine phosphatase non-receptor 22 polymorphism (PTPN22) with endometriosis: a meta-analysis
por: Pabalan, Noel, et al.
Publicado: (2017)

An In Silico Study Investigating Camptothecin-Analog Interaction with Human Protein Tyrosine Phosphatase, SHP2 (PTPN11)
por: Bajia, Donald, et al.
Publicado: (2023)

Non–lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells
por: Xu, Dan, et al.
Publicado: (2011)

Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity
por: Genera, Mariano, et al.
Publicado: (2023)

Protein tyrosine phosphatase nonreceptor 13 (PTPN13) is targeted by human papillomavirus 16 E6 in cervical epithelium
por: Nowicki, P, et al.
Publicado: (2009)

Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells
por: Clarke, Fiona, et al.
Publicado: (2017)

Association Between Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22) Polymorphisms and Risk of Ankylosing Spondylitis: A Meta-analysis
por: Meng, Xiantao, et al.
Publicado: (2017)

Deletion of protein tyrosine phosphatase, non-receptor type 4 (PTPN4) in twins with a Rett syndrome-like phenotype
por: Williamson, Sarah L, et al.
Publicado: (2015)

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains
por: Caillet-Saguy, Célia, et al.
Publicado: (2017)

Activating Mutations in Protein Tyrosine Phosphatase Ptpn11 (Shp2) Enhance Reactive Oxygen Species Production That Contributes to Myeloproliferative Disorder
por: Xu, Dan, et al.
Publicado: (2013)

Protein tyrosine phosphatase PTPN22 regulates IL‐1β dependent Th17 responses by modulating dectin‐1 signaling in mice
por: Purvis, Harriet A, et al.
Publicado: (2017)

Dissecting the role of His domain protein tyrosine phosphatase/PTPN23 and ESCRTs in sorting activated epidermal growth factor receptor to the multivesicular body
por: Tabernero, Lydia, et al.
Publicado: (2018)

Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) gene single nucleotide polymorphisms and its interaction with T2DM on pulmonary tuberculosis in Chinese Uygur population
por: Wang, Xian-Hua, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0h3eg34a6jrjnq0hm6mu5vn900