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Dynamic regulatory networks of T cell trajectory dissect transcriptional control of T cell state transition
T cells exhibit heterogeneous functional states, which correlate with responsiveness to immune checkpoint blockade and prognosis of tumor patients. However, the molecular regulatory mechanisms underlying the dynamic process of T cell state transition remain largely unknown. Based on single-cell tran...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577129/ https://www.ncbi.nlm.nih.gov/pubmed/34786214 http://dx.doi.org/10.1016/j.omtn.2021.10.011 |