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Dynamic regulatory networks of T cell trajectory dissect transcriptional control of T cell state transition

T cells exhibit heterogeneous functional states, which correlate with responsiveness to immune checkpoint blockade and prognosis of tumor patients. However, the molecular regulatory mechanisms underlying the dynamic process of T cell state transition remain largely unknown. Based on single-cell tran...

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Detalles Bibliográficos
Autores principales: Yan, Min, Hu, Jing, Yuan, Huating, Xu, Liwen, Liao, Gaoming, Jiang, Zedong, Zhu, Jiali, Pang, Bo, Ping, Yanyan, Zhang, Yunpeng, Xiao, Yun, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577129/
https://www.ncbi.nlm.nih.gov/pubmed/34786214
http://dx.doi.org/10.1016/j.omtn.2021.10.011