Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IX

BACKGROUND: The cell-surface enzyme carbonic anhydrase IX (CAIX/CA9) promotes tumor growth, survival, invasion, and metastasis, mainly via its pH-regulating functions. Owing to its tumor-specific expression, CAIX-targeting antibodies/chemicals are utilized for therapeutic and diagnostic purposes. Ho...

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Detalles Bibliográficos
Autores principales: Horikawa, Mei, Sabe, Hisataka, Onodera, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577137/
https://www.ncbi.nlm.nih.gov/pubmed/34742153
http://dx.doi.org/10.1016/j.tranon.2021.101258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577137/
https://www.ncbi.nlm.nih.gov/pubmed/34742153
http://dx.doi.org/10.1016/j.tranon.2021.101258

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