Cargando…

Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IX

BACKGROUND: The cell-surface enzyme carbonic anhydrase IX (CAIX/CA9) promotes tumor growth, survival, invasion, and metastasis, mainly via its pH-regulating functions. Owing to its tumor-specific expression, CAIX-targeting antibodies/chemicals are utilized for therapeutic and diagnostic purposes. Ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Horikawa, Mei, Sabe, Hisataka, Onodera, Yasuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577137/ https://www.ncbi.nlm.nih.gov/pubmed/34742153 http://dx.doi.org/10.1016/j.tranon.2021.101258

Ejemplares similares

Arf6-driven cell invasion is intrinsically linked to TRAK1-mediated mitochondrial anterograde trafficking to avoid oxidative catastrophe
por: Onodera, Yasuhito, et al.
Publicado: (2018)

The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis(†)
por: Sabe, Hisataka, et al.
Publicado: (2009)

Rab5c promotes AMAP1–PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion
por: Onodera, Yasuhito, et al.
Publicado: (2012)

Co-Overexpression of GEP100 and AMAP1 Proteins Correlates with Rapid Local Recurrence after Breast Conservative Therapy
por: Kinoshita, Rumiko, et al.
Publicado: (2013)

Imaging of carbonic anhydrase IX with an (111)In-labeled dual-motif inhibitor
por: Yang, Xing, et al.
Publicado: (2015)

AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions
por: Tien, Dat Nguyen, et al.
Publicado: (2014)

Global transcriptional response to carbonic anhydrase IX deficiency in the mouse stomach
por: Kallio, Heini, et al.
Publicado: (2010)

Carbonic anhydrase IX in oligodendroglial brain tumors
por: Järvelä, Sally, et al.
Publicado: (2008)

Targeting Carbonic Anhydrase IX Activity and Expression
por: Mahon, Brian P., et al.
Publicado: (2015)

Carbonic Anhydrase IX—Mouse versus Human
por: Takacova, Martina, et al.
Publicado: (2019)

Carbonic anhydrase IX and acid transport in cancer
por: Becker, Holger M.
Publicado: (2019)

High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer
por: Tsutaho, Akio, et al.
Publicado: (2020)

ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer
por: Hashimoto, Shigeru, et al.
Publicado: (2019)

Coordinated Regulation of Metabolic Transporters and Migration/Invasion by Carbonic Anhydrase IX
por: McDonald, Paul C., et al.
Publicado: (2018)

Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness
por: Ward, Carol, et al.
Publicado: (2018)

Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX
por: Koruza, Katarina, et al.
Publicado: (2020)

Carbonic Anhydrases II, IX, and XII in Reflux Esophagitis
por: Nortunen, Minna, et al.
Publicado: (2021)

Primary Duodenal Adenocarcinoma Expressing Carbonic Anhydrase IX
por: Kubo, Kimitoshi, et al.
Publicado: (2022)

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity
por: Oikawa, Tsukasa, et al.
Publicado: (2018)

Expression and prognostic value of carbonic anhydrase IX (CA-IX) in bladder urothelial carcinoma
por: Xiang, An-Ping, et al.
Publicado: (2022)

High level expression of AMAP1 protein correlates with poor prognosis and survival after surgery of head and neck squamous cell carcinoma patients
por: Sato, Hiroki, et al.
Publicado: (2014)

Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells
por: Handa, Haruka, et al.
Publicado: (2018)

Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosis
por: Doyen, Jérome, et al.
Publicado: (2013)

Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics
por: McDonald, Paul C., et al.
Publicado: (2012)

Circulating Carbonic Anhydrase IX and Antiangiogenic Therapy in Breast Cancer
por: Brown-Glaberman, Ursa, et al.
Publicado: (2016)

The Expression of Carbonic Anhydrases II, IX and XII in Brain Tumors
por: Haapasalo, Joonas, et al.
Publicado: (2020)

Carbonic anhydrase IX as a novel candidate in liquid biopsy
por: Ozensoy Guler, Ozen, et al.
Publicado: (2019)

Carbonic Anhydrase IX: A Renewed Target for Cancer Immunotherapy
por: de Campos, Najla Santos Pacheco, et al.
Publicado: (2022)

Structure and Dynamics of the Isozymes II and IX of Human Carbonic Anhydrase
por: Rai, Divya, et al.
Publicado: (2022)

Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients
por: Závada, J, et al.
Publicado: (2003)

Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX
por: Shao, Yangguang, et al.
Publicado: (2010)

The inhibitory effect of boric acid on hypoxia-regulated tumour-associated carbonic anhydrase IX
por: Yusuf, Zainab Saad, et al.
Publicado: (2022)

Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model
por: Otsuka, Yutaro, et al.
Publicado: (2018)

Inhibition of Carbonic Anhydrase IX Promotes Apoptosis through Intracellular pH Level Alterations in Cervical Cancer Cells
por: Temiz, Ebru, et al.
Publicado: (2021)

The role of carbonic anhydrase IX in cancer development: links to hypoxia, acidosis, and beyond
por: Pastorekova, Silvia, et al.
Publicado: (2019)

Expression of carbonic anhydrases IX and XII during mouse embryonic development
por: Kallio, Heini, et al.
Publicado: (2006)

Expression of carbonic anhydrase IX suggests poor outcome in rectal cancer
por: Korkeila, E, et al.
Publicado: (2009)

Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas
por: Viikilä, Pia, et al.
Publicado: (2016)

An update on anticancer drug development and delivery targeting carbonic anhydrase IX
por: Kazokaitė, Justina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_qknlj2shitl9krqp6eg9nq64p2