The formation and repair of DNA double-strand breaks in mammalian meiosis

Programmed DNA double-strand breaks (DSBs) are necessary for meiosis in mammals. A sufficient number of DSBs ensure the normal pairing/synapsis of homologous chromosomes. Abnormal DSB repair undermines meiosis, leading to sterility in mammals. The DSBs that initiate recombination are repaired as cro...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Wei, Liu, Cong, Xu, Ya-Ting, Xu, Yu-Min, Luo, Meng-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577251/
https://www.ncbi.nlm.nih.gov/pubmed/34708719
http://dx.doi.org/10.4103/aja202191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577251/
https://www.ncbi.nlm.nih.gov/pubmed/34708719
http://dx.doi.org/10.4103/aja202191

Ejemplares similares