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Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells

Azoospermia patients who carry a monogenetic mutation that causes meiotic arrest may have their biological child through genetic correction in spermatogonial stem cells (SSCs). However, such therapy for infertility has not been experimentally investigated yet. In this study, a mouse model with an X-...

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Detalles Bibliográficos
Autores principales: Wang, Ying-Hua, Yan, Meng, Zhang, Xi, Liu, Xin-Yu, Ding, Yi-Fu, Lai, Chong-Ping, Tong, Ming-Han, Li, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577253/
https://www.ncbi.nlm.nih.gov/pubmed/33533741
http://dx.doi.org/10.4103/aja.aja_97_20