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Perspectives on the translation of in-vitro studies to precision medicine in Cystic Fibrosis

Recent strides towards precision medicine in Cystic Fibrosis (CF) have been made possible by patient-derived in-vitro assays with the potential to predict clinical response to small molecule-based therapies. Here, we discuss the status of primary and stem-cell derived tissues used to evaluate the pr...

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Detalles Bibliográficos
Autores principales: Dumas, Marie-Pier, Xia, Sunny, Bear, Christine E., Ratjen, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577330/
https://www.ncbi.nlm.nih.gov/pubmed/34740114
http://dx.doi.org/10.1016/j.ebiom.2021.103660