Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes

Although mutant-specific T cells are elicited in some individuals infected with HIV-1 mutant viruses, the detailed characteristics of these T cells remain unknown. A recent study showed that the accumulation of strains expressing Nef135F, which were selected by HLA-A*24:02-restricted T cells, was as...

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Detalles Bibliográficos
Autores principales: Kuse, Nozomi, Murakoshi, Hayato, Akahoshi, Tomohiro, Chikata, Takayuki, James, Katherine L., Gatanaga, Hiroyuki, Rowland-Jones, Sarah L., Oka, Shinichi, Takiguchi, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577379/
https://www.ncbi.nlm.nih.gov/pubmed/34523962
http://dx.doi.org/10.1128/JVI.01259-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577379/
https://www.ncbi.nlm.nih.gov/pubmed/34523962
http://dx.doi.org/10.1128/JVI.01259-21

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