Cargando…
Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes
Although mutant-specific T cells are elicited in some individuals infected with HIV-1 mutant viruses, the detailed characteristics of these T cells remain unknown. A recent study showed that the accumulation of strains expressing Nef135F, which were selected by HLA-A*24:02-restricted T cells, was as...
Autores principales: | Kuse, Nozomi, Murakoshi, Hayato, Akahoshi, Tomohiro, Chikata, Takayuki, James, Katherine L., Gatanaga, Hiroyuki, Rowland-Jones, Sarah L., Oka, Shinichi, Takiguchi, Masafumi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577379/ https://www.ncbi.nlm.nih.gov/pubmed/34523962 http://dx.doi.org/10.1128/JVI.01259-21 |
Ejemplares similares
-
Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1
por: Zhang, Yu, et al.
Publicado: (2020) -
Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele
por: Zhang, Yu, et al.
Publicado: (2022) -
Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control
por: Murakoshi, Hayato, et al.
Publicado: (2018) -
Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8(+) T Cells and Accumulation of HLA-Associated Escape Mutations
por: Zhang, Yu, et al.
Publicado: (2021) -
Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens
por: Zou, Chengcheng, et al.
Publicado: (2019)