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Truncation of the Cytoplasmic Tail of Equine Infectious Anemia Virus Increases Virion Production by Improving Env Cleavage and Plasma Membrane Localization

Envelope glycoproteins (Envs) of lentiviruses harbor unusually long cytoplasmic tails (CTs). Natural CT truncations always occur in vitro and are accompanied by attenuated virulence, but their effects on viral replication have not been fully elucidated. The Env in equine infectious anemia virus (EIA...

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Detalles Bibliográficos
Autores principales: Wang, Xue-Feng, Wang, Yu-Hong, Bai, Bowen, Zhang, Mengmeng, Chen, Jie, Zhang, Xiangmin, Gao, Min, Wang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577380/
https://www.ncbi.nlm.nih.gov/pubmed/34495693
http://dx.doi.org/10.1128/JVI.01087-21