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Direct Activation of Endothelial Cells by SARS-CoV-2 Nucleocapsid Protein Is Blocked by Simvastatin

Emerging evidence suggests that endothelial activation plays a central role in the pathogenesis of acute respiratory distress syndrome (ARDS) and multiorgan failure in patients with coronavirus disease 2019 (COVID-19). However, the molecular mechanisms underlying endothelial activation in COVID-19 p...

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Detalles Bibliográficos
Autores principales: Qian, Yisong, Lei, Tianhua, Patel, Parth S., Lee, Chi H., Monaghan-Nichols, Paula, Xin, Hong-Bo, Qiu, Jianming, Fu, Mingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577385/
https://www.ncbi.nlm.nih.gov/pubmed/34549987
http://dx.doi.org/10.1128/JVI.01396-21