The NF-κB Transcriptional Footprint Is Essential for SARS-CoV-2 Replication

SARS-CoV-2, the etiological agent of COVID-19, is characterized by a delay in type I interferon (IFN-I)-mediated antiviral defenses alongside robust cytokine production. Here, we investigate the underlying molecular basis for this imbalance and implicate virus-mediated activation of NF-κB in the abs...

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Detalles Bibliográficos
Autores principales: Nilsson-Payant, Benjamin E., Uhl, Skyler, Grimont, Adrien, Doane, Ashley S., Cohen, Phillip, Patel, Roosheel S., Higgins, Christina A., Acklin, Joshua A., Bram, Yaron, Chandar, Vasuretha, Blanco-Melo, Daniel, Panis, Maryline, Lim, Jean K., Elemento, Olivier, Schwartz, Robert E., Rosenberg, Brad R., Chandwani, Rohit, tenOever, Benjamin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577386/
https://www.ncbi.nlm.nih.gov/pubmed/34523966
http://dx.doi.org/10.1128/JVI.01257-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577386/
https://www.ncbi.nlm.nih.gov/pubmed/34523966
http://dx.doi.org/10.1128/JVI.01257-21

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