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Estrogen inhibits renal Na-Pi Co-transporters and improves klotho deficiency-induced acute heart failure
OBJECTIVE AND HYPOTHESIS: Klotho is an aging-suppressor gene. Mutation of Klotho gene causes hyperphosphatemia and acute heart failure. However, the relationship of hyperphosphatemia and acute heart failure is unclear. We hypothesize that hyperphosphatemia mediates Klotho deficiency-induced acute he...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577443/ https://www.ncbi.nlm.nih.gov/pubmed/34678656 http://dx.doi.org/10.1016/j.redox.2021.102173 |