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Estrogen inhibits renal Na-Pi Co-transporters and improves klotho deficiency-induced acute heart failure

OBJECTIVE AND HYPOTHESIS: Klotho is an aging-suppressor gene. Mutation of Klotho gene causes hyperphosphatemia and acute heart failure. However, the relationship of hyperphosphatemia and acute heart failure is unclear. We hypothesize that hyperphosphatemia mediates Klotho deficiency-induced acute he...

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Detalles Bibliográficos
Autores principales:	Chen, Kai, Sun, Zhongjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577443/ https://www.ncbi.nlm.nih.gov/pubmed/34678656 http://dx.doi.org/10.1016/j.redox.2021.102173

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