Deficient immunoproteasome assembly drives gain of α-synuclein pathology in Parkinson's disease

Aberrant α-synuclein (α-Syn) accumulation resulting from proteasome dysfunction is considered as a prominent factor to initiate and aggravate the neurodegeneration in Parkinson's disease (PD). Although the involvement of 26S proteasome in proteostasis imbalance has been widely accepted, our kno...

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Detalles Bibliográficos
Autores principales: Bi, Mingxia, Du, Xixun, Xiao, Xue, Dai, Yingying, Jiao, Qian, Chen, Xi, Zhang, Lingqiang, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577461/
https://www.ncbi.nlm.nih.gov/pubmed/34662812
http://dx.doi.org/10.1016/j.redox.2021.102167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8577461/
https://www.ncbi.nlm.nih.gov/pubmed/34662812
http://dx.doi.org/10.1016/j.redox.2021.102167

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